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Updated: Jun 18, 2025

Identification of Intracellular Signaling Events Induced in Viable Cells by Interaction with Neighboring Cells Undergoing Apoptotic Cell Death
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聚菲林II通过激活Pyruvate Kinase M2诱导纤维瘤细胞的亡

Jun Wu1, Zhenjiang Ding2, Miao Zhong1

  • 1State Key Laboratory of Applied Organic Chemistry and College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, China.

Chemical research in toxicology
|July 27, 2024
PubMed
概括

聚菲林II (PP2) 激活酸激酶M2 (PKM2),这是有氧糖解中的关键酶. 这种激活通过扰乱糖解和诱导亡来抑制癌细胞的增殖和迁移,这表明PP2是潜在的纤维瘤瘤治疗方法.

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