在全膝关节关节整形术后恶心和吐时芳香疗法的结果
So Won Baek1, Jung Ho Noh2, Dongyun Lee3
1Nursing Department, Kangwon National University Hospital, Chuncheon-si, Gangwon-do, South Korea.
概括
在全膝关节整形术 (TKA) 后,胡香精芳香疗法有效地减少了术后恶心和吐 (PONV) 的抗使用. 衣草和油对抗食药的消费没有显著影响,所有组的患者满意度都相似.
科学领域:
- 麻醉学 麻醉学
- 疼痛管理 疼痛管理
- 补充医学是一种补充医学.
背景情况:
- 手术后恶心和吐 (PONV) 是在脊髓麻醉下进行全膝关节整形术 (TKA) 后的常见并发症.
- 有效的PONV管理对于患者的康复和满意度至关重要.
- 芳香疗法被探索为PONV.的非药物干预.
研究的目的:
- 评估使用衣草,和薄荷油进行芳香疗法在TKA后PONV管理中的有效性.
- 为了比较不同芳香疗法剂与安慰剂的有效性.
- 评估对抗药物消费和患者满意度的影响.
主要方法:
- 前性随机四臂安慰剂对照试验,涉及120名接受TKA的受试者.
- 组接受了手术后立即使用衣草,,薄荷或正常盐水 (安慰剂) 的芳香疗法.
- 评估了恶心和吐的严重程度 (哈尔恶心和吐量级),抗使用和患者满意度.
主要成果:
- 在手术后的第三天之前,两组之间恶心和吐得分 (HNV) 没有显著差异.
- 在胡油组中观察到明显较低的抗药物使用率 (P = .030).
- 在所有治疗组中,患者满意度水平是可比的 (P = .837).
结论:
- 用薄荷油进行芳香疗法可以减少对TKA后PONV的抗emetic需求.
- 衣草和芳香疗法没有显示出抗emetic使用的显著减少.
- 薄荷芳香疗法为PONV管理提供了一个可行的补充选择,具有良好的患者接受度.
相关概念视频
Chemotherapy-Induced Nausea and Vomiting: Neurokinin-1 Receptor Antagonists
157
Neurokinin 1 (NK1) receptors are distributed across the GI tract, vagal afferents, and key CNS regions including the central vomiting center and chemoreceptor trigger zone (CTZ) Chemotherapy agents stimulate enterochromaffin cells in the gastrointestinal (GI) tract to release large amounts of substance P (SP). SP is a neuropeptide released by specific sensory nerves in response to many different stressors, including those in the GI mucosa affected by chemotherapy. SP binds and activates...
157
Chemotherapy-Induced Nausea and Vomiting: Cannabinoids
208
Tetrahydrocannabinol (THC) is a phytocannabinoid that primarily interacts with the CB1 receptor, a type of G protein-coupled receptor (GPCR) predominantly in and around the chemoreceptor trigger zone (CTZ) and emetic center. THC also blocks the serotonin receptor activity in the dorsal vagal complex (DVC) by inhibiting serotonin release. THC exerts its anti-emetic effects through these interactions, which are beneficial for patients undergoing chemotherapy.
Two synthetic agonists of THC,...
Two synthetic agonists of THC,...
208
Chemotherapy-Induced Nausea and Vomiting: 5-HT3 Receptor Antagonists
187
5-HT3 receptor antagonists, such as dolasetron, granisetron (Kytril), ondansetron (Zofran), and palonosetron (Axoli), are crucial in managing chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea. These drugs selectively block 5-HT3 receptors in the visceral vagal and spinal afferent nerves, chemoreceptor trigger zone, and the vomiting center. They have a rapid onset of action and can be given as a single dose before chemotherapy. Ondansetron and granisetron, in particular,...
187
Chemotherapy-Induced Nausea and Vomiting: Dopamine Receptor Antagonists
240
Dopamine receptor antagonists, also known as antipsychotic agents, are critical in managing chemotherapy-induced vomiting. These antiemetic agents block dopamine receptors in the chemoreceptor trigger zone (CTZ), inhibiting signal transmission to the vomiting center. Antipsychotic agents encompass phenothiazines (PTZ), butyrophenones, benzamides, and thienobenzodiazepines (Zyprexa), which are utilized for their antiemetic and sedative properties.
Phenothiazines, such as prochlorperazine...
Phenothiazines, such as prochlorperazine...
240
Skeletal Muscle Relaxants: Therapeutic Uses
477
Skeletal muscle relaxants are used to relax muscle tone and alleviate painful muscle contractions. However, the choice of skeletal muscle relaxants depends on the duration of the surgical procedure in order to minimize potential side effects. Skeletal muscle relaxants like neuromuscular blocking agents [NMBAs] are commonly employed as adjuvants alongside general anesthetics in clinical settings. NMBAs are also used to maintain controlled ventilation during surgery of the larynx or pharynx...
477


