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相关概念视频

Penis01:29

Penis

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The penis serves a dual role in sexual reproduction and urination. It consists of three main regions: the glans penis, the body, and the root, each with distinct functions and unique anatomical features.
Anatomy of the Penis
The glans penis, or the head, is the terminal part of the penis and houses the external urethral orifice, the exit point for urine and semen. Covered by the prepuce, or foreskin, the glans is noted for its sensitivity and plays a key role in sexual pleasure. The body of the...
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Male Sexual Response: Erection & Ejaculation01:17

Male Sexual Response: Erection & Ejaculation

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Sexual stimulation can take various forms, such as physical touch and visual or auditory cues. When this happens, the parasympathetic reflex in the sacral portion of the spinal cord is activated. This reflex stimulates the release of nitric oxide (NO), which then dilates the arterioles in the penis, increasing blood flow to the erectile tissues - the corpora cavernosa and corpus spongiosum.
The blood filling the erectile tissues compresses the veins, which helps to prevent blood from leaving...
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Disorders of the Male Reproductive System01:20

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Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
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相关实验视频

Updated: May 4, 2026

Droplet Barcoding-Based Single Cell Transcriptomics of Adult Mammalian Tissues
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VisualZoneR:一种计算协议,用于识别使用R的单细胞空间转录组的分区区域.

Thomas Kerzel1, Stefano Beretta1, Luigi Naldini2

  • 1San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.

STAR protocols
|July 27, 2024
PubMed
概括
此摘要是机器生成的。

本研究介绍了VisualZoneR,这是一种基于R的方法,用于分析空间转录学数据. 它识别出不同的组织区域并测量转录组变化,有助于理解复杂的生物环境.

关键词:
生物信息学是一种生物信息学.癌症 癌症 癌症 癌症基因表达 基因表达一个单细胞单细胞.

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科学领域:

  • 生物信息学是一种生物信息学.
  • 基因组学就是基因组学.
  • 计算生物学 计算生物学

背景情况:

  • 像Visium和Visium HD这样的空间转录技术可以生成复杂的数据集.
  • 分析组织内的隔间区域对于理解生物过程至关重要.
  • 现有的方法可能无法完全捕捉空间转录组数据的细微差别.

研究的目的:

  • 在单细胞空间转录组学数据中提出一个用于识别单元区区的协议.
  • 展示VisualZoneR用于分析组织异质性的应用.
  • 为了能够在确定的区域内测量转录组变化.

主要方法:

  • 使用VisualZoneR,一个基于R的技术.
  • 处理来自Visium或Visium HD的空间转录数据.
  • 识别不同的组织区域 (例如,健康的肝脏,转移性区域).
  • 整合多个样本并根据边界的近距离分组转录点.

主要成果:

  • 在组织样本中成功识别出不同的隔间区域.
  • 量化不同区域的转录基因变化.
  • 展示VisualZoneR分析空间关系和组织微环境的能力.

结论:

  • VisualZoneR提供了一个强大的框架来分析空间转录学数据.
  • 该协议有助于识别组织部分和相关的基因表达模式.
  • 这种方法增强了对生物组织空间异质性的理解.