Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

The Placebo Effect01:54

The Placebo Effect

6.1K
The placebo effect occurs when people's expectations or beliefs influence or determine their experience in a given situation. In other words, simply expecting something to happen can actually make it happen.
6.1K
Lipid-Lowering Drugs: Statins and Miscellaneous Agents01:20

Lipid-Lowering Drugs: Statins and Miscellaneous Agents

613
Hyperlipidemia, a medical condition often referred to as high cholesterol, is characterized by abnormally elevated levels of lipids in the bloodstream. When present in excess, these lipids, specifically cholesterol and triglycerides, can lead to serious health complications, often involving cardiovascular diseases. Illnesses like atherosclerosis, heart attacks, and pancreatitis have all been linked to untreated hyperlipidemia. This means controlling and regulating cholesterol and triglyceride...
613
Blind Procedures02:07

Blind Procedures

10.6K
Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which...
10.6K
Blinding01:11

Blinding

2.4K
Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.
2.4K
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

124
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
124
Drugs for Treatment of Constipation-Predominant IBS01:21

Drugs for Treatment of Constipation-Predominant IBS

151
Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
151

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

A vision for an academic health science centre: A survey of research engagement and barriers.

PloS one·2026
Same author

Interventions to improve adherence to clinical practice guidelines when treating cardiovascular disease: a systematic review.

Irish journal of medical science·2025
Same author

Factors influencing patients to choose one obesity treatment over another: a qualitative study.

International journal of obesity (2005)·2025
Same author

Semaglutide and blood pressure: an individual patient data meta-analysis.

European heart journal·2024
Same author

Exploring the readiness of the Irish healthcare system to adopt advanced therapies: a scoping review protocol.

Regenerative medicine·2024
Same author

Risk Factors and Modifiers for Cardiovascular Disease Assessment of Patients with Heterozygous Familial Hypercholesterolaemia.

Journal of clinical medicine·2024

相关实验视频

Updated: Jun 18, 2025

How to Study Placebo Responses in Motion Sickness with a Rotation Chair Paradigm in Healthy Participants
08:50

How to Study Placebo Responses in Motion Sickness with a Rotation Chair Paradigm in Healthy Participants

Published on: December 14, 2014

9.3K

立方体不耐受性和德鲁塞博效应

B Mugawar1, S Mcerlean2, P O' Connor1,3

  • 1Department of Pharmacology, Trinity College Dublin School of Medicine, Trinity Centre for Health Sciences, St James's Hospital, Dublin, Ireland.

QJM : monthly journal of the Association of Physicians
|July 27, 2024
PubMed
概括

静止素不耐受,包括与静止素相关的肌肉症状,增加心血管风险. 教育患者关于负面德鲁塞博效应和他类药物的好处,可以提高坚持并降低风险.

更多相关视频

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles
09:15

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles

Published on: November 10, 2017

14.6K
A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
04:30

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

Published on: May 14, 2013

25.5K

相关实验视频

Last Updated: Jun 18, 2025

How to Study Placebo Responses in Motion Sickness with a Rotation Chair Paradigm in Healthy Participants
08:50

How to Study Placebo Responses in Motion Sickness with a Rotation Chair Paradigm in Healthy Participants

Published on: December 14, 2014

9.3K
Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles
09:15

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles

Published on: November 10, 2017

14.6K
A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
04:30

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

Published on: May 14, 2013

25.5K

科学领域:

  • 心脏病学 心脏病学
  • 药理学 药理学是指药理学的学科.
  • 患者的坚持 患者的坚持

背景情况:

  • 高胆固醇血症是动脉样硬化心血管疾病的重要危险因素.
  • 类药物是高胆固醇血症的主要治疗方法.
  • 达他林不耐受 (SI),特别是达他林相关肌肉症状 (SAMS),导致治疗中止和心血管风险升高.

研究的目的:

  • 讨论他类药物不耐受 (SI) 的挑战.
  • 探索SAMS中负面德鲁塞博效应的作用.
  • 建议干预措施来管理SI和改善他类药物坚持.

主要方法:

  • 本评论回顾了关于他类药物不耐受性和负面德鲁塞博效应的现有文献.
  • 它综合了有关患者教育和遵守策略的信息.
  • 它讨论了减轻SI的潜在干预措施.

主要成果:

  • 一个显著的SAMS部分可能源于负面的Drucebo效应,受患者期望的影响.
  • 对SI和负德鲁塞博效应的患者教育至关重要.
  • 积极主动的管理策略可能会改善他类药物的坚持.

结论:

  • 解决患者的期望和负面的德鲁塞博效应对于管理SI至关重要.
  • 在开始他类药物治疗时有效的患者教育可以提高患者的坚持.
  • 针对SI的干预措施可以减轻与他类药物不坚持相关的心血管风险.