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在前部循环中风患者的内血管血栓切除术后,功能网络的重组

Tongyue Li¹, Jiaona Xu², Luoyu Wang³

¹Center for Cognition and Brain Disorders, the Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang, China; Zhejiang Key Laboratory for Research in Assessment of Cognitive Impairments, Hangzhou, Zhejiang, China.

NeuroImage. Clinical

|July 27, 2024

概括

血管内血栓切除术改善了急性缺血性中风患者的大脑网络功能. 更好的再注射与功能连接的改变相关,有助于评估中风恢复.

科学领域:

神经科学是一个神经科学.
放射学放射学是一门学科.
医疗成像医学成像

背景情况:

血管内血栓切除术是急性缺血性中风 (AIS) 的经过验证的治疗方法.
血栓切除术后的大脑网络重组及其与再输血的联系仍然不清楚.

研究的目的:

在AIS患者内血管内血栓切除术后调查功能性大脑网络变化.
探索反射范围和网络变化之间的关联.

主要方法:

休息状态fMRI数据分析了静态和动态功能连接 (FC).
在AIS患者中的四个高级功能网络 (DAN,VAN,ECN,DMN) 与健康对照 (HC) 进行了比较.
根据再输血状态,检查了患者子组中的FC差异.

主要成果:

与HC相比,AIS患者在关键的大脑网络中显示出改变的静态和动态FC.
改善的反与前皮内增加的静态FC和改变的动态FC相关.
观察到的网络变化与中风严重程度和功能恢复相关.

结论:

血栓切除术后的功能网络变化可以作为成像生物标志物.
这些发现可以为AIS患者进行血栓切除术后的定制康复策略提供信息.

关键词:

急性缺血性中风是一次急性缺血性中风.功能性大脑网络功能性大脑网络功能连接性的功能连接性.静止状态功能磁共振成像技术进行血栓切除术 (thrombectomy).

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