库尔库明-金属有机框架的物理特性和抗氧化活性
Li-Hang Chen1, Tao Chen1, Ru-Nan Zhao1
1SKL of Marine Food Processing & Safety Control, National Engineering Research Center of Seafood, Collaborative Innovation Center of Seafood Deep Processing, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, China.
Food chemistry
|July 27, 2024
概括
新型的素-金属-有机框架 (MOFs) 显示出营养物质传递的前景. 这些MOF表现出稳定性和抗氧化性质,有效抑制分解后的炎症反应.
科学领域:
- 材料科学 材料科学 材料科学
- 食品科学 食品科学 食品科学
- 纳米技术 纳米技术
背景情况:
- 金属有机框架 (MOF) 为食品中的功能成分提供了机会.
- 挑战包括优化装载能力和维持功能活动.
- 和提供健康益处,使它们适合增强MOF应用.
研究的目的:
- 为潜在的食品工业应用合成和表征黄MOF.
- 评估这些新型MOF的稳定性,负载能力和抗氧化特性.
- 评估MOFs分解后的抗炎作用.
主要方法:
- 微波辅助合成库尔库-MOFs. 在微波中辅助合成库尔库-MOF.
- 在各种pH值,盐度和温度下评估MOF的稳定性.
- 使用DPPH,ABTS和H2O2测定对抗氧化能力的评估.
- 在体外抗炎试验中,使用LPS刺激的RAW264.7细胞进行了抗炎试验.
主要成果:
- 微波合成实现了23.2±4.5%的收益率.
- MOFs在pH 4-10中表现出稳定性,并在PBS中逐渐分解.
- 抗氧化剂测试表明自由基的清除能力有所不同.
- 在酸性条件下MOF分解或存在H2O2 (≥10μM) 导致TNF-α分泌的显著抑制.
结论:
- 库尔库明-MOFs在微波的帮助下得到有效的合成.
- 这些MOF表现出有利的稳定性和抗氧化潜力.
- 在分解后,这些MOF有效地抑制LPS诱导的TNF-α分泌,这表明它们具有抗炎性质.
- 这些新的MOF材料具有在食品部门增强营养供应的潜力.
相关概念视频
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Group 1 elements are soft and shiny metallic solids. They are malleable, ductile, and good conductors of heat and electricity. The melting points of the alkali metals are unusually low for metals and decrease going down the group, while the density increases going down the group with the exception of potassium (Table 1).
Table 1: Properties of the alkali metals
Table 1: Properties of the alkali metals
02:32Bonding in Metals
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02:58Properties of Transition Metals
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01:23Properties of Organometallic Compounds
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