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Updated: Jun 18, 2025

Cecal Ligation and Puncture-induced Sepsis as a Model To Study Autophagy in Mice
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Published on: February 9, 2014

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皮奥格利塔通过SIRT1信号通路改善了与败血症相关的脑病变

Alaa H Shehata1, Aliaa F Anter1, Sara Mohamed Naguib Abdel Hafez2

  • 1Department of Pharmacology and Toxicology, Faculty of Pharmacy, Minia University, Minia, Egypt.

International immunopharmacology
|July 27, 2024
PubMed
概括

皮奥格利塔 (PIO) 通过激活PPARγ/SIRT1通路,可以预防败血症引起的脑损伤和神经行为障碍. 这种治疗可以提高生存率并减少炎症,这表明SIRT1在败血症相关脑病变中起着关键作用.

关键词:
在Caspase-3中使用.这就是HMGBGB.只有一个是 Iba1 .这就是MODs.在NLRP3中,NLRP3是NLRP3中的一个.神经行为缺陷 神经行为缺陷皮奥格利塔是如何使用的在SAE的SAE.一个SIRT1系统.败血症 这是一种败血症.我们的 iNOS iNOS

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