使用2017年ACC/AHABP指南对老年人心血管事件风险的BP分类
Yuta Suzuki1, Hidehiro Kaneko2, Akira Okada3
1The Department of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan; Center for Outcomes Research and Economic Evaluation for Health, National Institute of Public Health, Saitama, Japan.
Journal of cardiology
|July 27, 2024
概括
第1期高血压增加了60岁以上的成年人心血管疾病的风险. 降低缩血压可能会降低中风风险,但对于75岁以上的人来说,需要进一步研究.
科学领域:
- 心脏病学 心脏病学
- 老年病的医生 老年病的医生
- 公共卫生 公共卫生
背景情况:
- 在老年人中,第一阶段高血压和心血管疾病 (CVD) 风险之间的联系尚不清楚.
- 降低血压 (BP) 对这一人口群体的第一阶段高血压的益处是未知的.
研究的目的:
- 在60岁及以上的个体中调查第一阶段高血压和心血管疾病风险之间的关联.
- 探索BP降低对该人群中心血管疾病事件的影响.
主要方法:
- 一项队列研究利用了DeSC数据库 (n=476,654) 的日本全国数据.
- 参与者根据2017年ACC/AHABP指南进行了分类.
- 主要结局是综合性心血管疾病事件 (心肌梗塞,胸痛,中风,心力衰竭),平均随访时间为3.1年.
主要成果:
- 第1阶段高血压与10%的复合心血管疾病事件风险增加有关 (HR 1.10).
- 具体风险包括心肌梗塞 (HR 1.16),胸痛 (HR 1.06),中风 (HR 1.13) 和心力衰竭 (HR 1.13).
- 静脉血压降低≥5mmHg与中风风险降低相关;在≥75岁的人群中,这种关联较弱.
结论:
- 第1期高血压在老年人中具有显著的心血管疾病风险.
- 当前的ACC/AHABP指南可能适用于老年人群,但对于75岁以上的个人需要进一步验证.
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