在成年人群中发现的非肌痛性脑内脊髓脊髓脂瘤
Andrew M Hersh1, Ali Bydon1, Zach Pennington2
1Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
World neurosurgery
|July 27, 2024
概括
骨髓内脊髓脂瘤虽然罕见且良性,但会导致神经系统缺陷. 潜在的激光技术辅助的亚总切除,提供了安全有效的治疗方法,改善了大多数成年患者的治疗结果.
科学领域:
- 神经外科 神经外科
- 脊髓瘤学 脊髓瘤学
- 神经学 神经学
背景情况:
- 脊髓内皮质瘤 (ISCLs) 是一种罕见的良性瘤.
- 由于粘附于脊髓,它们可能导致显著的神经缺陷.
- 手术切除具有挑战性,但对于症状管理来说是必要的.
研究的目的:
- 审查在没有脊髓失色症的成年人中进行ISCL切除的机构经验.
- 报告ISCLs的手术治疗后的长期结果.
- 评估ISCLs的亚总切除的安全性和有效性.
主要方法:
- 对接受ISCL切除的成年患者的回顾性审查 (2011年6月至2023年6月).
- 排除患有脊柱失色症或额外骨髓脂瘤的患者.
- 纳入标准:显微镜外科手术脱皮,经过组织病理学确认.
主要成果:
- 确定了6名成年患者 (平均年龄35.0±11.5岁,67%为女性).
- 四个瘤是胸部;常见的症状包括疼痛,麻木和运动软弱.
- 五名患者在手术后实现了独立的行走;一名患者因瘤进展需要重新手术.
结论:
- 亚总切除是ISCLs的安全有效治疗方法.
- 手术技术,如脱,外生成分切除和激光辅助脱,可以改善结果.
- 大多数患者经历症状改善和预防进一步的神经衰退.
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