来自生物医疗设备,植入物和金属的接触性皮肤炎 - 从内部的问题
Karin A Pacheco1, Jacob P Thyssen2
1Division of Environmental & Occupational Health Sciences, National Jewish Health, Denver, Colo; Environmental & Occupational Health Division, Colorado School of Public Health, Aurora, Colo.
概括
对生物医疗植入物的内部反应,如骨科设备,可以引起类似于过敏接触性皮肤炎的症状. 本综述涵盖了这些与植入物相关的免疫反应的诊断和治疗.
科学领域:
- 免疫学 免疫学 免疫学
- 材料科学 材料科学 材料科学
- 生物医学工程 生物医学工程
背景情况:
- 过敏接触性皮肤炎涉及对低分子量化学物质的免疫反应,这些化学物质通常存在于金属,防腐剂和粘合剂中.
- 这些过敏原在内部生物医学设备中使用时会引起敏感和炎症.
- 对内部装置的反应可能表现为胀,疼痛,硬,运动范围减少或.
研究的目的:
- 审查报告的皮肤和骨科植入物局部内部反应.
- 讨论对其他医疗器械的免疫反应,包括心脏器械,血管支架和牙科植入物.
- 总结诊断工具,解释共识和与植入物相关反应的治疗策略.
主要方法:
- 报道病例的文献综述和对内部生物医学器械过敏反应的研究.
- 分析用于识别与植入物相关的过敏症的诊断方法.
- 综合目前用于管理植入物诱导炎症的治疗策略.
主要成果:
- 骨科植入物是与免疫反应相关的内部金属设备的主要类别.
- 反应可以从局部化的内部症状到外部接触性皮肤炎.
- 不同的医疗器械,包括心脏和牙科植入物,也可以引起免疫反应.
结论:
- 含有过敏原的内部生物医学设备可以触发类似于外部接触性皮肤炎的免疫反应.
- 对于患有植入物相关反应的患者来说,准确的诊断和适当的管理至关重要.
- 需要进一步的研究和标准化的诊断/治疗方案.
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