在外层皮层中,围性视觉错位的神经相关物
Geyu Weng1,2, Amir Akbarian2, Kelsey Clark2
1Department of Biomedical Engineering, University of Utah, Salt Lake City, UT, USA.
Nature communications
|July 27, 2024
概括
眼睛运动期间的视觉偏差,即围眼错位,是由外层区域的神经机制解释的. 这项研究揭示了视觉区域如何优先考虑萨卡德目标表示,影响空间感知.
科学领域:
- 神经科学是一个神经科学.
- 计算神经科学是一种神经科学.
- 视觉感知 视觉感知 视觉感知
背景情况:
- 斜视眼动 (斜视) 导致斜视眼错位,改变视觉刺激的感知.
- 这种视觉空间变化的神经基础以及它与其他形现象的关系仍然不清楚.
研究的目的:
- 为了研究围绕萨卡德目标 (ST) 基础上的围绕萨卡德空间偏差的神经机制.
- 将外层神经元活动与空间感知中观察到的行为偏差联系起来.
主要方法:
- 来自的外层区域的电生理学记录.
- 基于神经元的时空灵敏度来量化空间偏差的计算模型的开发.
- 模型预测与行为数据的相关性.
主要成果:
- 计算模型成功地预测了ST周围的周周空间偏差,与行为观测保持一致.
- 确定了负责表示偏差的特定神经元响应组件.
- 证明了与ST相距的受体场的神经元的增强敏感性驱动ST空间偏差.
结论:
- 外层区域在通过优先考虑saccade目标表示来产生perisaccadic空间偏差方面发挥着至关重要的作用.
- 视觉区域分配资源以增强ST表示,可能导致短暂的空间扭曲.
- 这些发现表明,外层神经元在构建感知刺激位置方面起着一般作用.
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