一个叙述性回顾缺血性priapism初始治疗的叙述性回顾
Supanut Lumbiganon1,2, Muhammed A Moukhtar Hammad1, Babak Azad1
1Department of Urology, University of California, Irvine, CA, USA.
International journal of impotence research
|July 27, 2024
概括
缺血性priapism需要及时治疗,以防止阴茎组织损伤. 第一线治疗包括注射烯和吸收,尽管较短的病例缺乏明确的管理指南.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 紧急医疗 紧急医疗
背景情况:
- 偏爱症涉及与性活动无关的长期,痛苦的勃起.
- 缺血性priapism是最常见的类型和医疗紧急情况.
- 迅速干预至关重要,以防止不可逆转的勃起组织损伤.
研究的目的:
- 审查缺血性priapism的初始管理策略.
- 为突出当前的治疗建议和挑战.
主要方法:
- 对现有文献和指导方针进行叙述性审查.
- 分析一线和替代治疗选择.
主要成果:
- 内内注射和吸入 (有或没有灌) 是建议的第一线治疗方法.
- 管理因临床背景和患者因素而有所不同.
- 准则提供了明确的建议,用于priapism>4小时.
结论:
- 缺血性priapism的初始管理侧重于及时干预.
- 有限的证据挑战了短期前症的管理.
- 需要进一步的研究,以优化对较短时间的病例进行最佳治疗.
相关概念视频
01:28Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors
141
Phosphodiesterase 5 (PDE5) inhibitors are potent enzymes that function to hydrolyze cyclic nucleotides to their corresponding 5' monophosphates. Their unique biochemical properties have been applied in treating Pulmonary Arterial Hypertension (PAH).
Among the PDE5 inhibitors, sildenafil (Revatio) stands out as a competitive and selective inhibitor. It operates by elevating cellular levels of cGMP and augmenting signaling through the cGMP-PKG pathway, promoting vasodilation. Upon oral...
Among the PDE5 inhibitors, sildenafil (Revatio) stands out as a competitive and selective inhibitor. It operates by elevating cellular levels of cGMP and augmenting signaling through the cGMP-PKG pathway, promoting vasodilation. Upon oral...
141
01:23Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists
165
Prostacyclin receptor agonists are a class of therapeutic agents integral to managing pulmonary arterial hypertension (PAH). These drugs operate by mimicking the action of prostaglandin I2, or PGI2, a naturally occurring compound in the body.
These agonists bind to the IPR receptor situated on the plasma membrane of the pulmonary artery smooth muscle cells. This binding triggers a cascade of reactions known as the GS-AC-cAMP-PKA pathway. This pathway results in the relaxation of smooth muscle...
These agonists bind to the IPR receptor situated on the plasma membrane of the pulmonary artery smooth muscle cells. This binding triggers a cascade of reactions known as the GS-AC-cAMP-PKA pathway. This pathway results in the relaxation of smooth muscle...
165