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Updated: Jun 18, 2025

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在单细胞RNA测序数据中推断新细胞

Ziyi Li1, Peng Yang2

  • 1Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. zli16@mdanderson.org.

Methods in molecular biology (Clifton, N.J.)
|July 27, 2024
PubMed
概括

单细胞RNA测序 (scRNA-seq) 可进行基因表达分析. 这项研究提出了三种新的方法,可以从scRNA-seq数据中推断出新的细胞类型,帮助生物学发现.

关键词:
副本数量变化的变化新型细胞检测新型细胞检测一个单细胞RNA-seqq.有监督的注释.没有监督的集群.

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相关概念视频

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RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while...
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