COVID-19对大学生内皮功能,动脉硬和血压的长期影响:一项前后对照研究
Jianwei Peng1, Wenhuang Guo1, Peilun Li1
1Guangdong Provincial Key Laboratory of Physical Activity and Health Promotion, Guangzhou Sport University, 1268 Middle Guangzhou Avenue, Guangzhou, 510500, Guangdong, China.
BMC infectious diseases
|July 27, 2024
概括
COVID-19对大学生血管健康产生了负面影响,损害了内皮功能,并长期增加了血压. 虽然动脉硬会随着时间的推移而改善,但感染后的血压可能会恶化.
科学领域:
- 心血管研究研究心血管研究
- 传染病对传染病的影响
- 学生健康 学生健康
背景情况:
- COVID-19带来心血管风险,对大学生的长期影响尚不清楚.
- 在年轻人感染COVID-19后调查持续的血管变化至关重要.
研究的目的:
- 评估COVID-19对大学生动脉硬,内皮功能和血压的长期影响.
- 在学生群体中确定SARS-CoV-2感染后心血管后果的持续时间和性质.
主要方法:
- 注册37名大学生COVID-19感染持续超过2个月.
- 通过手臂动脉流介导扩张 (FMD) 评估内皮功能.
- 使用ABI Systems 100评估动脉硬度,测量了脚-手腕指数 (ABI),手腕-脚脉冲波速率 (baPWV),大动脉-股骨脉冲波速率 (cfPWV),心率 (HR) 和血压 (BP).
主要成果:
- 在COVID-19后观察到口病的显著减弱 (p < 0.001) 和cfPWV和静脉血压 (SBP) 的增加 (p < 0.05).
- 随着时间的推移,动脉硬度 (baPWV) 得到改善 (p < 0.01),但腹筋血压 (DBP) 增加 (p < 0.05).
- 没有发现ABI或HR的显著变化,也没有发现与其他变量的相关性 (p > 0.05).
结论:
- 在大学生中,COVID-19感染会对血管功能产生持久的有害影响.
- 虽然动脉硬显示出改善的趋势,但在感染后,血压可能会遵循相反的轨迹.
- 研究结果强调,在COVID-19恢复后,需要监测学生的心血管健康.
相关概念视频
Factors affecting Blood pressure
3.1K
Several physiological and lifestyle factors influence blood pressure (BP). Understanding these factors is crucial as they are significant in patient education and blood pressure management.
Physiological Factors:
Physiological Factors:
3.1K
Psychoneuroimmunology: Cardiovascular Disease
29
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
A key area of focus in PNI is the relationship between stress and coronary...
29
Longitudinal Studies
151
Longitudinal studies are also widely used in other medical and social science fields. For instance, in cardiovascular research, they can monitor patients' health over decades to identify risk factors for heart disease, such as high cholesterol or smoking, and evaluate the long-term effectiveness of preventive measures. Similarly, in mental health studies, researchers might follow individuals from adolescence into adulthood to understand the development and progression of conditions like...
151
Stress and Mental Health
94
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
Individuals with depression often experience challenges in both their personal and professional...
94
Hypertension and Regulation of Blood Pressure
2.0K
Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
2.0K
Exercise and Cardiovascular Response
765
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
765


