视网膜静脉封闭患者的维生素D缺乏:系统性审查和元分析
Kimia Daneshvar1, Mohammadreza Akhlaghi2, Shila Iranpour1
1Isfahan Eye Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
International journal of retina and vitreous
|July 27, 2024
概括
维生素D缺乏与视网膜静脉封闭 (RVO) 的更高风险有关. 患有RVO的患者显示维生素D水平明显降低,这表明维生素D在疾病中的作用.
科学领域:
- 眼科医生 眼科 眼科
- 内分泌学 在内分泌学.
- 营养科学 营养科学
背景情况:
- 视网膜静脉封闭 (RVO) 是视力丧失的一个重要原因.
- 维生素D和RVO之间的关系需要进一步澄清.
研究的目的:
- 系统地审查和分析有关维生素D水平与RVO之间的关联的现有文献.
- 要确定维生素D缺乏是否是RVO的危险因素.
主要方法:
- 观察性研究的系统审查和元分析.
- 在PubMed,SCOPUS,Web of Science和Embase数据库中进行了搜索.
- 包括6项研究,589名参与者.
主要成果:
- 维生素D缺乏会显著增加RVO的风险 (OR=14.51,P=0.014).
- 在RVO患者中,血清维生素D水平降低了1.91 ng/mL (P<0.001).
- 中央RVO和分支RVO亚型之间的维生素D水平没有显著差异.
结论:
- 维生素D缺乏症在RVO患者中比健康个体更为普遍.
- 强调维生素D补充剂在RVO预防和治疗中的潜在作用.
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