精神分裂症的睡眠呼吸暂停:估计患病率和对认知的影响
Stephen Edward Ghazikhanian1, Toral S Surti2
1Department of Psychiatry, Yale University School of Medicine, 300 George Street, New Haven, CT, 06515, USA.
Journal of psychiatric research
|July 28, 2024
概括
许多精神分裂症患者没有被诊断为阻塞性睡眠呼吸暂停 (OSA). 虽然报告的OSA与更好的认知相关,但预测的OSA表明认知功能更差,这表明寻求治疗可能会影响结果.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 睡眠医学 睡眠医学
背景情况:
- 精神分裂症与显著的认知缺陷有关.
- 未经治疗的疾病可能会加剧精神分裂症的认知障碍.
- 阻塞性睡眠呼吸暂停 (OSA) 影响了与精神分裂症相关的认知领域,并且可以治疗.
研究的目的:
- 为了估计患有精神分裂症的退伍军人中OSA的患病率.
- 在这个人群中调查OSA和认知/功能能力之间的关联.
- 基于自我报告的结果与预测OSA高风险的结果进行比较.
主要方法:
- 评估了3942名患有精神分裂症的退伍军人样本.
- 通过自我报告和预测模型来确定OSA的患病率.
- 各组之间对神经心理和功能能力评估进行了比较.
主要成果:
- 报告的OSA患病率为14%,而72%的预测是高风险.
- 自我报告的OSA与更好的认知和功能表现有关.
- 预测的OSA与处理速度,口头学习和工作记忆的较低得分相关.
结论:
- 许多患有精神分裂症的退伍军人可能有未被诊断的OSA.
- 自我报告的OSA可能反映出更好的健康寻求行为.
- 精神分裂症的认知障碍可能会因未经治疗的OSA而恶化,这凸显了查的必要性.
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