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Updated: Jun 18, 2025

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阴离子代谢产物是由人体CYP3A4A4由丁丁尼布形成的

Shimon Nakashima1, Tatsuki Fukami2, Takashi Kudo3

  • 1Drug Metabolism and Toxicology, Faculty of Pharmaceutical Sciences, Kanazawa University, Kanazawa, Japan.

Drug metabolism and pharmacokinetics
|July 28, 2024
PubMed
概括

研究人员确定了宁泰达尼布的潜在反应性代谢物,iminium离子,由人体肝脏中的细胞染色体P450 3A4 (CYP3A4) 形成. 这一发现可能有助于澄清因丁丹尼布引起的肝损伤的原因.

关键词:
在 CYP3A4 中.离子是离子的一种.尼丁达尼比是什么意思反应性代谢物反应性代谢物

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