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晚期髓性甲状腺癌因COVID-19患者持续升高的公素水平而被发现
Ines Bucci1,2, Giulia Di Dalmazi2, Cesidio Giuliani1
1Department of Medicine and Aging Sciences, Center for Advanced Studies and Technology (CAST), G.d'Annunzio University Chieti-Pescara, Chieti, Italy.
Endocrinology, diabetes & metabolism case reports
|July 28, 2024
概括
在COVID-19患者中,高甲激素水平表明甲状腺髓性癌 (MTC). 先进的MTC可能进展缓慢,卡博桑提尼布有效地管理了患者.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 核医学是一种核医学.
背景情况:
- 通常与细菌感染相关的高甲素 (proCt) 水平也可能表明甲状腺髓性癌 (MTC).
- 区分与感染相关的和与MTC相关的血清升高对于准确的诊断和及时的治疗至关重要.
研究的目的:
- 在COVID-19住院期间报告一例髓状甲状腺癌 (MTC) 病例,最初呈现出高甲水平.
- 突出卡尔西托尼和成像在识别高级MTC的诊断实用性.
- 评估卡博赞提尼布在治疗晚期转移性MTC的疗效.
主要方法:
- 一个88岁的男性因COVID-19而住院的病例研究,患有持续高甲水平.
- 血清素测量,超声波,细针吸收 (FNA) 和18F-fluorodopa PET/CT扫描用于诊断和分期.
- 用卡博赞提尼布治疗远程转移的晚期MTC.
主要成果:
- 该患者被诊断为晚期MTC,转移到肋骨,脊椎,下翼和肝脏.
- 卡博桑提尼布治疗导致16个月的疾病稳定,功能自主性得到保护.
- 血清酸水平仍然很高,但成像显示没有疾病进展.
结论:
- 即使在感染的背景下,持续的高甲素水平也需要对MTC进行调查.
- 先进的MTC可能会表现出惰的过程,并且可以通过向治疗,如卡博赞提尼布,有效地管理.
- 卡博桑提尼布在控制晚期MTC方面表现出有效性,为无法切除的疾病提供了有价值的治疗选择.
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