药剂师主导干预措施在骨关节感染多学科咨询会议中的影响
Anne Elisabeth Royere1, Xavier Pourrat1, Louis-Romée Le Nail2
1Pharmacy Department, Logipôle Trousseau, CHRU Tours, France.
Infectious diseases now
|July 28, 2024
概括
药剂师在多学科骨关节感染 (BJI) 会议上显著减少了与药物有关的问题. 他们的干预改善了复杂BJI病例中的抗生素治疗和患者安全.
科学领域:
- 药理学 药理学是指药理学的学科.
- 传染性疾病 传染性疾病
- 临床药房 临床药房
背景情况:
- 骨关节感染 (BJIs) 需要密集的抗生素治疗,通常会在脆弱的患者中引起不良影响.
- 在参考中心举行的多学科团队会议对于管理复杂的BJI案件至关重要.
研究的目的:
- 评估药剂师参与多学科团队会议对BJI患者药物相关问题的影响.
- 评估药物干预措施 (PI) 在优化抗生素治疗和患者结果方面的有效性.
主要方法:
- 进行了一项单一中心的前后比较研究.
- 药剂师在多学科团队会议上确定和记录了与药物有关的问题.
- 药物干预措施被一个由传染病学家和药剂师组成的委员会追溯评估.
主要成果:
- 60名患者被纳入干预组,59名患者为对照组,主要是患有复杂BJIs的老年人.
- 74%的患者接受了口服抗生素治疗,只有5.9%的患者因不良反应再次入院.
- 进行了62个试验试验,主要针对药物相互作用 (46%) 和剂量调整 (42%),两组之间的关键性没有显著差异.
结论:
- 药剂师参与BJI多学科团队会议有效防止与药物有关的问题.
- 药剂师,外科医生和传染病学家之间的合作提高了患者的安全性,并优化了复杂BJI的治疗.
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