未来的多中心研究,以验证重症监护患者的胃肠功能障碍评分 (GIDS):国际GUTPHOS研究A部分的研究协议
Imre W K Kouw1, Max Melchers1, Merli Mändul2
1Department of Intensive Care Medicine, Gelderse Vallei Hospital, Ede, the Netherlands; Wageningen University & Research, Division of Human Nutrition and Health, Wageningen, the Netherlands.
这项研究验证了重症患者的胃肠功能障碍评分 (GIDS). 该项目旨在改善在重症监护病房 (ICU) 中对胃肠道功能障碍的评估.
科学领域:
- 关键护理医学 关键护理医学
- 胃肠病学 胃肠病学
- 临床研究方法论 临床研究方法论
背景情况:
- 胃肠道 (GI) 功能障碍在重症患者中很普遍.
- 目前还没有统一的,前性验证的肠胃功能障碍评分系统.
- 胃肠功能障碍评分 (GIDS) 已开发,但需要验证.
研究的目的:
- 为了前性验证最近开发的胃肠功能障碍评分 (GIDS).
- 在接受重症监护单位 (ICU) 的成年患者的多中心队列中评估GIDS.
- 在死亡率和依赖性结果方面评估GIDS.
主要方法:
- GUTPHOS研究是一项前性,多中心,非干预性队列研究.
- 大约有1400名成年ICU患者每天都会被监测,以检测消化道功能障碍的迹象和症状.
- 将GIDS与28日和90天全因死亡率的初级结果以及包括ICU/住院停留时间和依赖性的二级结果进行测试.
主要成果:
- 该部分尚未提供,因为研究仍在进行中.
- 该研究旨在在2024年1月至6月期间收集数据.
- 主要结局是28日和90日全因死亡率.
结论:
- 瓜特福斯研究是世界上第一个在成年ICU患者中前性验证GIDS的研究.
- 对GIDS的验证对于其在未来的干预研究中使用至关重要.
- 一个经过验证的GIDS将促进研究,因为缺乏标准化的消化道功能障碍测量工具而受到阻碍.
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