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Updated: Jun 18, 2025

Author Spotlight: Developing Tools to Tune the Activity of Tyrosine Phosphatases
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Published on: September 6, 2024

342

蛋白质氨酸酸酶通过反应性氧物种的调节

Colin L Welsh1, Lalima K Madan2

  • 1Department of Cell and Molecular Pharmacology & Experimental Therapeutics, College of Medicine, Medical University of South Carolina, Charleston, SC, United States.

Advances in cancer research
|July 28, 2024
PubMed
概括

蛋白氨酸酸酶 (PTPs) 对于细胞信号传递至关重要,对氧化应激敏感. 本综述详细介绍了活性氧物种 (ROS) 如何可逆和不可逆地氧化PTP,影响其功能.

关键词:
半氨酸 (cysteine) 是一种氨酸.氧化过程中的氧化.在 PTP PTP PTP 中.这就是PTP1B.酸酶非激活的过程蛋白质氨酸酸酶是一种蛋白质氨酸酸酶.这就是ROSOS ROS.有反应性氧物种的反应性氧物种.在 SHP2 中, SHP2 是 SHP2.

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