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Updated: Jun 18, 2025

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
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Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents

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加拿大白金 (IV) 复合物 向表皮-介质细胞过渡作为抗增殖和抗转移剂

Yan Chen1, Ming Zhang1, Yanqin He1

  • 1Institute of Biopharmaceutical Research, Liaocheng University, Liaocheng 252059, P.R. China.

Journal of medicinal chemistry
|July 29, 2024
PubMed
概括

新的加拿大 ((IV) 结合物抑制上皮层-介质细胞过渡 (EMT),抑制瘤转移,并通过激活免疫反应和DNA损伤来增强抗瘤免疫力. 这些药物为治疗转移性癌症提供了一个有希望的策略.

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