肌酸补充对成人的认知功能的影响:系统性审查和元分析
Chen Xu1, Siyuan Bi1, Wenxin Zhang1
1School of Physical Education, Guizhou Normal University, Guiyang, China.
Frontiers in nutrition
|July 29, 2024
概括
肌酸单水合物补充剂对增强成年人的记忆力,注意力和处理速度有前途. 需要进一步的研究来证实所有认知领域和人群的益处.
科学领域:
- 神经科学是一个神经科学.
- 营养科学 营养科学
- 老年学是一门学科.
背景情况:
- 认知能力下降是老年人群日益关注的一个问题.
- 肌酸单酸是一种受欢迎的补充剂,具有潜在的神经保护性质.
- 了解肌酸对认知的影响对于制定预防策略至关重要.
研究的目的:
- 系统地审查和分析肌酸单对成年人认知功能的影响.
- 探索肌酸在预防和延迟认知障碍相关疾病中的潜在作用.
- 评估对记忆,执行功能,注意力和处理速度的影响.
主要方法:
- 按照PRISMA 2020指南进行系统审查和元分析.
- 包括来自主要数据库 (PubMed,Scopus,Web of Science) 的随机对照试验 (RCT),发表于1993-2024.
- 使用标准化平均差异 (SMD) 和Hedge的g与95%的置信区间 (CI) 来评估认知领域.
主要成果:
- 分析了16个具有492名参与者的RCT.
- 在记忆,注意力时间和处理速度方面观察到显著的积极影响.
- 整体认知功能或执行功能没有显著改善.
- 患有疾病的个体,18-60岁的成年人和女性的好处更为明显.
结论:
- 肌酸单酸补充剂对特定的认知功能,特别是记忆,注意力和处理速度有潜在的益处.
- 对整体认知功能和执行功能的证据需要进一步调查.
- 建议进行更大,更强大的临床试验,以验证发现并探索潜在机制.
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