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通常使用的贝叶斯多样化方法导致在经验类型学上的分支特定率的生物学上有意义的差异
Jesús Martínez-Gómez1,2,3, Michael J Song1,4, Carrie M Tribble1,5
1Department of Integrative Biology and the University Herbarium, University of California, Berkeley, CA, United States.
Evolution letters
|July 29, 2024
概括
遗传学中的多样化速率转移取决于方法. 五种贝叶斯方法往往产生不同的物种化和灭绝率,影响宏观进化解释.
科学领域:
- 进行比较的遗传学.
- 宏观进化的生物学
- 遗传学上的比较方法.
背景情况:
- 识别沿着血统的多样化速率的变化对于理解进化事件至关重要.
- 有许多方法可以估计多元化率并检测转变,但它们的准确性和适当的使用仍在争论中.
- 这些变化可以与形态创新,适应性特征,基因组变化或分散事件有关.
研究的目的:
- 为了比较五种贝叶斯式方法推断多元化速率转移的结果.
- 评估贝叶斯对宏观进化混合物分析 (BAMM),血统特异性出生死亡转移 (LSBDS),PESTO,多类型出生死亡 (MTBD) 和克拉多遗传多样化速率转移 (ClaDS2) 模型的可比性.
- 评估不同的方法如何影响对宏观进化动态的解释.
主要方法:
- 五种贝叶斯系遗传学方法应用于65种经验时间校准的基因组.
- 在不同方法中比较推断的物种化率,灭绝率和净多样化率.
- 分析导致不同结果的基本模型差异.
主要成果:
- 五种贝叶斯方法经常产生不同的估计物种,灭绝和净多样化率.
- 不同的速率估计可能导致对宏观进化动态的对比解释.
- 对多元化利率变化的推理在很大程度上取决于所选择的方法.
结论:
- 生物学家应该使用多种方法来证实发现,或者选择基于其模型假设与其经验系统一致的方法.
- 了解特定方法的偏差对于准确解释多元化率转移至关重要.
- 遗传学比较方法的选择对宏观进化研究的结论产生了重大影响.
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