过度活跃膀 (OAB) 症状在接受灵活囊镜检查的患者中
Rafiullah Khan1, Syed M Nazim1, Shahid Iqbal2
1Surgery, Aga Khan University Hospital, Karachi, PAK.
Cureus
|July 29, 2024
概括
灵活的囊镜可以暂时恶化过活的膀 (OAB) 症状,有时会导致新发的OAB. 这些症状通常在几天内自行消失,有助于患者咨询和未来的管理策略.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 患者的治疗结果.
背景情况:
- 过度活性膀 (OAB) 症状可以显著影响生活质量.
- 柔性囊镜是一种常见的泌尿器科手术.
研究的目的:
- 为了测量OAB症状在柔性囊镜后的变化.
- 评估手术后新出现的OAB症状的发生率.
主要方法:
- 一项前性观察性研究,涉及63名接受灵活囊镜检查的成年患者.
- 使用OAB-V8工具在手术前和手术后的第一和第四天评估的OAB症状.
- 根据分数,患者被分类为OAB阴性 (<8) 或OAB阳性 (≥8).
主要成果:
- 术后第1天 (p<0.01) 平均OAB得分显著增加,但在第4天 (p=0.08) 恢复到基线.
- OAB阳性从手术前的33.3%增加到手术后的50.8%,其中26.2%出现了新的症状.
- 年龄,性别,适应症和α阻断剂的使用并没有显著影响OAB得分的变化.
结论:
- 灵活的囊镜可以暂时加剧或触发OAB症状.
- 在手术后出现新的OAB症状很常见,但通常会消失.
- 结果可以为患者的咨询和管理策略提供信息,在囊镜术后对OAB进行管理.
相关概念视频
The Micturition Reflex
531
Urination, or micturition involves the coordination of the bladder's detrusor muscle and two sphincters to ensure controlled bladder emptying.
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating...
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating...
531
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
154
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
154
Urinary Bladder
520
The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
520
Disorders of the Urinary System
274
The urinary system is responsible for eliminating waste and excess fluids from the body. However, disorders of the urinary system can arise due to various reasons like infections, stress, age, congenital abnormalities, and lifestyle.
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
274
Drugs for Treatment of Constipation-Predominant IBS
151
Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
151
Drugs for Treatment of Diarrhea-Predominant IBS
156
Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
156


