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在接受全甲状腺切除术治疗的格雷夫斯病患者体重和组成的变化
Takashi Fukuda1, Seigo Tachibana1, Tomohiro Osako2
1Department of Endocrinology, Yamashita Thyroid Hospital, Fukuoka City, JPN.
Cureus
|July 29, 2024
概括
对格雷夫斯病的甲状腺切除术导致有利的体重增加,主要来自增加的骨肌肉质量. 这一发现有助于医生向患者保证治疗后身体组成的变化.
科学领域:
- 内分泌学 在内分泌学.
- 代谢医学是一种代谢医学.
- 手术科学 手术科学
背景情况:
- 甲状腺毒性,通常是由格雷夫斯病引起的,增加能量消耗,导致减肥.
- 患有格雷夫斯病的患者可能会担心与治疗相关的体重增加,这会影响他们接受手术的意愿.
- 了解治疗后的身体成分变化对于患者咨询至关重要.
研究的目的:
- 为了研究在患有格雷夫斯病的患者中全甲状腺切除术后体重和组成的变化.
- 为咨询患者提供有关手术后预期体重变化的数据.
主要方法:
- 研究了一组21名患有格雷夫斯病的患者,他们接受了全甲状腺切除术.
- 患者被分为甲状腺功能高 (n=9) 和甲状腺功能低 (n=12) 的手术前组.
- 在手术前和手术后5个月使用生物电阻分析评估了体重,身高和身体组成.
主要成果:
- 在手术后,所有患者的体重,体重指数和骨肌肉质量都显著增加,但脂肪质量没有显著增加.
- 组A (手术前甲状腺上升) 显示骨肌肉质量显著增加.
- B组 (手术前的甲状腺功能) 显示脂肪质量显著增加.
- 在手术前甲状腺功能和骨肌肉质量的变化之间观察到正相关性.
结论:
- 在Graves病患者的甲状腺全切除术使甲状腺功能正常化,并与体重增加有关.
- 观察到的体重增加主要是由于骨肌肉质量的增加.
- 这些发现支持咨询患者,术后体重增加是有益的,主要反映了改善的肌肉质量.
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