昆达利尼对认知功能和记忆的影响:对随机对照试验的系统审查
Selvaraj Giridharan1, Nagaraj V Kumar2, Rajanee Bhana3
1Oncology, Tawam Hospials, Al Ain, ARE.
Cureus
|July 29, 2024
概括
昆达利尼 (KY) 显示了改善老年人的认知功能和记忆力的承诺. 这种做法还提供神经生物学上的好处,包括情绪提升和增加大脑连接,支持其在认知健康计划中的使用.
科学领域:
- 神经科学是一个神经科学.
- 老年学是一门学科.
- 综合医学是一个整体的医学.
背景情况:
- 认知衰退和痴呆症带来了重大的公共卫生挑战.
- 寻求非药物干预来改善老年人群的认知功能.
- 昆达利尼 (KY) 正因其潜在的认知和神经生物学益处而受到探索.
研究的目的:
- 系统地审查昆达利尼 (KY) 对老年人的认知功能的影响.
- 评估KY对记忆,神经生物学标志物和心理结果的影响.
- 评估KY作为一种干预措施,用于那些面临认知衰退和痴呆症风险的人.
主要方法:
- 从2000年1月到2023年12月的随机对照试验 (RCT) 的系统文献搜索.
- 包括5个RCT,涉及215名轻度认知障碍或主观认知衰退的老年人 (≥55岁).
- 对比KY干预与记忆增强训练 (MET) 或精神教育.
主要成果:
- 昆达利尼持续改善记忆性能和执行功能.
- 观察到情绪显著改善,海马体积增加,神经连接性改善.
- KY降低了促炎性细胞因子,改变了与衰老相关的基因表达.
结论:
- 昆达利尼显示出作为一种有效的干预措施,在高风险的老年人中增强认知,情绪和神经生物学健康的潜力.
- 现有证据支持将KY纳入认知健康计划.
- 需要进一步的广泛,精心设计的RCT来确认发现并优化干预策略.
相关概念视频
Role of Cerebellum and Prefrontal Cortex in Memory
404
The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...
404
Higher Mental Functions of Brain: Learning and Memory
718
Memory is one of the most vital higher mental functions of the brain. Memory is closely related to learning because it enables us to retain information and experiences from our past to use them in our present life. It also helps us to remember facts, events, and skills, such as riding a bike or swimming. There are two types of memory — declarative memory, which involves memorizing facts or events, and procedural memory, which enables us to remember how to do something like writing or...
718
Cognitive Development During Adulthood
73
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
73
Role of Hippocampus in Memory
202
The hippocampus, a critical brain structure, plays an essential role in memory processing, particularly in the formation and retrieval of memory. This small, seahorse-shaped region is located within the medial temporal lobe, with one hippocampus in each brain hemisphere. Experimental studies involving lesions in the hippocampi of rats have demonstrated significant impairments in tasks such as object recognition and maze navigation, indicating the hippocampus involvement in both recognition and...
202
Cognitivism
1.4K
Cognitive psychology emerged as a significant field in the mid-20th century. It focused on understanding humans' internal mental processes. This approach emphasizes how people perceive, remember, think, and solve problems—elements critical to human cognition.
Previously dominated by behaviorism, which prioritized observable behaviors and largely ignored mental processes, psychology transformed in the 1950s. Cognitive psychologists argue that understanding how we think and process...
Previously dominated by behaviorism, which prioritized observable behaviors and largely ignored mental processes, psychology transformed in the 1950s. Cognitive psychologists argue that understanding how we think and process...
1.4K
Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists
114
Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.
114


