在Helicobacter pylori阴性患者的胃内细菌感染和内镜发现
Takashi Kawai1, Yusuke Kawai1, Yoshika Akimito1
1Department of Gastroenterological Endoscopy, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.
Journal of clinical biochemistry and nutrition
|July 29, 2024
概括
非Helicobacter pylori (H. pylori) 细菌感染在H. pylori阴性患者中很常见,并可能导致胃炎症. 这些感染与特定的内镜发现有关,特别是在使用胃抗分泌药物的人群中.
科学领域:
- 胃肠病学 胃肠病学
- 微生物学 微生物学
- 内镜检查是指内镜检查.
背景情况:
- 杆菌 (H. pylori) 是胃炎的主要原因.
- 其他细菌在H.pylori阴性患者的胃炎中的作用仍然不太清楚.
研究的目的:
- 研究非H. pylori胃细菌感染与H. pylori阴性个体内镜检测结果之间的关联.
- 为了确定与这些替代性细菌感染相关的特定内镜特征.
主要方法:
- 对105名 H. pylori 阴性患者进行了内镜检查和胃汁培养.
- 用京都胃炎分类来评估内镜检测结果.
- 使用统计分析 (单变量和多变量) 来评估关联.
主要成果:
- 细菌培养在65.7%的患者中呈阳性,其中包括甲型血溶性链球菌和Neisseria sp. 这是最普遍的.
- 在细菌培养结果与胃抗分泌药物使用,缩性胃炎,肠道代谢和粘膜胀等因素之间发现了显著的关联.
- 多变量分析强调粘膜胀是与非H. pylori细菌相关的关键内镜发现,特别是在使用胃抗分泌药物的患者中.
结论:
- 非H. pylori细菌可以感染胃并诱导胃炎症.
- H. pylori 阴性患者的胃炎可能受到细菌存在的影响,特别是在长期使用胃抗分泌药物时.
- 非H. pylori细菌性胃炎的内镜检测结果与感染H. pylori的胃炎不同.
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