用于在吸收不良状态中激发的语言下阿塞纳:三例患者病例
Bradley G Burk1,2,3, Kyle Humphreys4, Jim Waites2
1University of Alabama at Birmingham Medical Center, Department of Pharmacy, JT1728, 619 19th Street South, Birmingham, AL 35222, USA.
Therapeutic advances in psychopharmacology
|July 29, 2024
概括
舌下 (SL) 氨酸为患有胃吸收不良的患者管理激动提供了一个有希望的替代方案. 这种口服药物绕过肠道,在复杂的病例中显示出有效性,尽管适当的管理至关重要.
科学领域:
- 精神病学是一个精神病学.
- 胃肠病学 胃肠病学
- 药理学 药理学是指药理学的学科.
背景情况:
- 胃的吸收不良条件阻碍了口服药物的疗效.
- 在吸收不良的患者中,管理激动的选择有限.
- 舌下 (SL) 的阿塞纳可以通过粘膜吸收,绕过胃肠道.
研究的目的:
- 为了评估SL asenapine在激动的胃吸收不良患者中的疗效和安全性.
- 探索医疗复杂的患者激动的替代口服治疗方法.
主要方法:
- 一系列病例报告了三名患有短肠综合症,病毒性胃炎和大动脉剖析等疾病的患者.
- 患者在其他抗精神病药物失败后接受SL阿森因激动治疗.
- 评估的结果包括减少动荡和不良影响.
主要成果:
- 这三名患者在1-5天内都经历了显著的激动减轻.
- 没有报告任何不良影响.
- 在两名患者中,药物的不当吞降低了SL asenapine的生物可用性.
结论:
- 在胃吸收质疑的患者中,SL asenapine是激发的可行选择.
- 临床医生应考虑SL asenapine用于医学复杂的激动患者.
- 对这一群体需要进一步的指导方针和替代剂量形式.
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