对新发炎标志物预测复杂尾炎的能力进行比较
Ali Saridas1, Nafis Vural2, Murat Duyan3
1Department of Emergency Medicine, Prof. Dr. Cemil Tascioglu City Hospital, Istanbul, Turkey.
Open medicine (Warsaw, Poland)
|July 29, 2024
概括
该研究发现,虽然其他生物标志物如NLR,SII,SIRI和PIV对于复杂的尾炎是有效的,但血红蛋白,白蛋白,淋巴细胞和血小板 (HALP) 评分显示了对不复杂的尾炎的合理诊断能力.
科学领域:
- 医学诊断 医学诊断 医学诊断
- 炎症生物标志物 炎症生物标志物
背景情况:
- 急性尾炎 (AA) 是急性腹痛的主要原因之一.
- 区分复杂的 (CA) 和不复杂的尾炎 (UCA) 对于患者的管理至关重要.
研究的目的:
- 评估血红蛋白,白蛋白,淋巴细胞和血小板 (HALP) 和修改的HALP (m-HALP) 评分在区分CA和UCA的诊断疗效.
- 为了比较HALP和m-HALP得分与其他炎症生物标志物的性能.
主要方法:
- 在急诊室诊断出AA的436名成年患者的回顾性分析.
- 患者被分为复杂尾炎 (CA) 和非复杂尾炎 (UCA) 组.
- 使用接收器操作特征 (ROC) 分析来确定诊断切线.
主要成果:
- 包括中性细胞与淋巴细胞比率 (NLR),全身免疫炎症指数 (SII),全身炎症反应指数 (SIRI) 和泛免疫炎症值 (PIV) 在内的生物标志物证明了CA的可接受诊断能力.
- HALP和m-HALP得分在检测UCA方面表现出相当大的诊断能力 (AUC分别为0.64和0.68).
结论:
- 虽然PIV,SIRI,SII和NLR对于诊断CA是有效的,但HALP和m-HALP得分为UCA提供了公平的诊断实用性.
- 进一步的研究可能会探索这些标记物的联合实用性,以改善尾炎的诊断.
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