斯派克N354糖化增强SARS-CoV-2适应性通过结构性可塑性的人类适应性

Pan Liu1,2, Can Yue1, Bo Meng3

  • 1CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.

PubMed
概括

新的SARS-CoV-2变种在尖端蛋白的受体结合域 (RBD) 中获得了糖化. 在BA.2.86亚系中这种N354糖化减少了传染性,但通过多种机制增强了病毒适应性.

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