对4D磁共振成像技术的系统审查,用于腹部放射治疗治疗计划
Lamyaa Aljaafari1,2,3, David Bird2, David L Buckley1
1Leeds Institute of Cardiovascular & Metabolic Medicine (LICAMM), University of Leeds, Woodhouse, Leeds, LS2 9JT, United Kingdom.
Physics and imaging in radiation oncology
|July 29, 2024
概括
四维磁共振成像 (4DMRI) 显示了腹部放射治疗的前景,可能会改善瘤定义和运动评估,而不是四维计算机断层扫描 (4DCT). 然而,临床实施需要进一步验证和标准化.
科学领域:
- 放射治疗 物理 物理
- 医疗成像医学成像
- 在瘤学瘤学.
背景情况:
- 四维计算机断层扫描 (4DCT) 是腹部放射治疗治疗计划 (RTP) 中运动管理的标准.
- 四维磁共振成像 (4DMRI) 正成为腹部RTP运动管理的潜在替代方案.
- 本综述评估了关于腹部RTP的4DMRI的当前文献,重点关注技术方面和临床有效性.
研究的目的:
- 审查和评估关于4DMRI在腹部放射治疗治疗计划中的现有文献.
- 评估在接受放射治疗的患者中使用4DMRI的技术考虑和临床有效性.
- 为了比较4DMRI与当前标准的潜在好处,4DCT.
主要方法:
- 按照PRISMA指南进行系统的文献审查.
- 在Medline,Embase,Scopus和Web of Science数据库中搜索到2023年12月31日.
- 基于4DMRI重建方法的分类研究:从3DMRI获取和从多片2DMRI获取.
主要成果:
- 分析了39项研究,表明4DMRI有潜力通过改善瘤定义和运动评估来增强腹部RTP,与4DCT相比.
- 从3DMRI采集中重建的4DMRI显示了在腹部RTP中运动管理的可行性,提供了良好的空间分辨率.
- 从多切片2DMRI收购中重建的4DMRI目前具有不适合临床使用的切片厚度.
- 临床实施的障碍包括有限的商业解决方案和4DCT缺乏大型比较研究.
结论:
- 4DMRI显示了改善腹部放射治疗治疗计划的潜力.
- 需要进一步制定标准和指导方针,以便在放射治疗方案中确定4DMRI的临床益处.
- 解决技术限制和进行比较研究对于广泛的临床采用至关重要.
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