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Updated: Jun 18, 2025

Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells
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Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells

Published on: April 26, 2017

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该Rbfox1/LASR复合体通过识别多部分RNA调节模块来控制替代的mRNA前剪接

Parham Peyda, Chia-Ho Lin, Kelechi Onwuzurike

    bioRxiv : the preprint server for biology
    |July 29, 2024
    PubMed
    概括

    Rbfox/LASR复合体使用多种动机结合RNA,而不仅仅是GCAUG. 这揭示了蛋白质复合体如何通过协同RNA元素解码组合拼接信号.

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