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Updated: Jun 18, 2025

Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods
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信号和转录动态是早期适应致癌性BRAF抑制的基础

Cameron T Flower, Chunmei Liu, Hui-Yu Chuang

    bioRxiv : the preprint server for biology
    |July 29, 2024
    PubMed
    概括

    药物诱导的适应导致对抗癌激酶抑制剂的耐药性. 准SRC家族激酶 (SFK) 信号,以补偿BRAF抑制,为黑色素瘤提供了一个潜在的治疗策略.

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