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Updated: Jun 18, 2025

Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation
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Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation

Published on: June 17, 2015

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JAK2/STAT3信号通路在小鼠星球细胞神经元C8-D1A细胞系中介甲基毒性

Aafia Ahmed, Michael Aschner, Beatriz Ferrer

    bioRxiv : the preprint server for biology
    |July 29, 2024
    PubMed
    概括

    甲基 (MeHg) 神经毒性通过抑制信号转换器和转录3 (STAT3) 激活器而恶化. STAT3激活保护星细胞免受MeHg诱导的损伤,这表明它是缓解中毒的关键因素.

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