视觉系统的结构和功能连接在面部观看时在身体形障碍中.
Wan-Wa Wong1,2, Hayden Peel1,3, Ryan Cabeen4
1Centre for Addiction and Mental Health, Toronto, ON, Canada.
bioRxiv : the preprint server for biology
|July 29, 2024
概括
患有身体形障碍 (BDD) 的人在垂直尾囊中表现出改变的白质,影响视觉处理和外表不满. 这表明了BDD中独特的功能结构关系.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 神经成像是一种神经成像.
背景情况:
- 身体形障碍 (BDD) 的特点是扭曲的外表感知.
- 全球和局部视觉处理中的不平衡可能是BDD的基础.
- 垂直的尾囊集成视觉信息,但其在BDD中的作用尚不清楚.
研究的目的:
- 在BDD中研究垂直的尾带白质微观结构.
- 检查与心理测量措施和有效连接的关联.
- 在BDD中探索功能结构关系.
主要方法:
- 扩散MRI和fMRI数据分析了17名患有BDD的成年人和21名对照人群.
- 捆绑特异性分析量化了垂直的头囊神经元密度和方向分散.
- 在面部查看任务中计算的有效连接.
主要成果:
- 在BDD中,较低的神经元密度与更高的外表不满和较低的有效连接度相关.
- 更糟糕的BDD症状和洞察力与较弱的有效连接性有关.
- 白质微观结构没有显著的群体差异;对照组没有相关性.
结论:
- 在BDD中垂直尾带神经元密度降低可能会损害视觉信息整合.
- 研究结果表明,改变的微观结构与BDD中的外观感知有关.
- 在BDD中可能存在明显的功能结构关系.
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