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Updated: Jun 18, 2025

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孕激素通过整合素αvβ3依赖途径在孕激素受体阴性MDA-MB-231细胞中调节细胞生长

Chung-Che Tsai1,2, Yung-Ning Yang3,4, Kuan Wang2

  • 1Graduate Institute of Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan.

Heliyon
|July 29, 2024
PubMed
概括

孕激素通过激活整合素αvβ3-ERK1/2通路来刺激PR阴性乳腺癌细胞的生长. 这一途径改变了基因表达,推动了这些癌细胞的增殖.

关键词:
乳腺癌是什么? 乳腺癌是什么整体素 αvβ3 的含量孕激素 (Progesterone) 是一种激素.孕激素受体是什么? 孕激素受体是什么?核武器的扩散

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