心脏骤停和心脏性休克复杂化ST段升高心肌梗塞在中国:一个回顾性多中心研究
Shao-Shuai Liu1, Juan Wang2, Hui-Qiong Tan3,4
1Department of Cardiology, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, 758 Hefei Road, Qingdao, Shandong, 266035, China.
Heliyon
|July 29, 2024
概括
心脏骤停 (CA) 和心脏性休克 (CS) 在中国的ST段升高心肌梗塞 (STEMI) 患者中显著增加了30天死亡率和不良事件. CA和CS的组合构成最高风险,强调需要迅速干预.
科学领域:
- 心脏病学 心脏病学
- 临床医学 临床医学
- 公共卫生 公共卫生
背景情况:
- 关于心脏骤停 (CA) 和心脏性休克 (CS) 对ST段升高心肌梗塞 (STEMI) 的中国患者的综合影响的数据有限.
- 了解这些影响对于改善高风险人群的预后至关重要.
研究的目的:
- 评估经历CA和/或CS的STEMI患者的临床结果.
- 在STEMI患者中识别与CA或CS相关的风险因素.
主要方法:
- 这是一项对中国7468名连续STEMI患者的队列研究.
- 患者被分为四个组:CA + CS,只有CA,只有CS,没有CA或CS.
- 考克斯比例危险回归分析用于评估30天的所有原因死亡和主要不良心血管事件.
主要成果:
- 心脏骤停 (CA) 和心脏性休克 (CS) 分别发生在4.4%和5.0%的患者中,其中1.6%的患者经历了两者.
- 30天死亡率和主要不良心血管事件的发生率在各组显著增加:没有CA或CS,只有CS,只有CA,和CA + CS.
- 与没有CA或CS的患者相比,患有CA和CS的患者面临所有原因死亡 (HR 25.259) 和主要不良心血管事件 (HR 19.098) 的风险最高.
结论:
- 大约11%的中国STEMI患者经历了CA,CS或两者兼而有之.
- 这些情况独立地与30天死亡率和主要心血管不良事件的风险大幅增加有关.
- 这些发现突显了CA和CS对中国人口STEMI预后的关键影响.
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