在患有慢性炎症性呼吸道疾病的患者中,甘油三指数和肉症之间存在关联
Xinping Yang1,2, Lifang Li2, Ruina Li2
1Shanxi Medical University, Taiyuan, Shanxi 030000, China.
Heliyon
|July 29, 2024
概括
甘油三糖 (TyG) 指数与患有慢性炎症性呼吸道疾病 (CIAD) 的患者的萨尔科佩尼亚风险有关. 较高的TyG指数水平表明患上萨科佩尼亚的可能性增加,这表明其作为预测标记物的潜力.
科学领域:
- 代谢综合征研究 代谢综合征研究
- 肺部医学 肺部医学
- 老年病的医生 老年病的医生
背景情况:
- 慢性炎症性呼吸道疾病 (CIAD) 与各种代谢并发症有关.
- 随着年龄的增长,肌肉质量和力量的丧失,即萨尔科佩尼亚,是慢性病患者日益关注的问题.
- 甘油三糖 (TyG) 指数正在成为胰岛素抵抗和代谢功能障碍的标志物.
研究的目的:
- 调查三甘-葡萄糖 (TyG) 指数与被诊断患有慢性炎症性呼吸道疾病 (CIAD) 的患者中沙科佩尼亚风险之间的关联.
主要方法:
- 利用了来自国家健康和营养检查调查 (2011-2018) 的数据,其中包括981名CIAD患者.
- 使用多重逻辑回归评估了TyG指数三角动物和肉症风险之间的相关性.
- 用人接收器运行特征 (ROC) 曲线分析和线性回归以评估TyG指数和肉症之间的预测值和关系.
主要成果:
- 在对混因素进行调整后,TyG指数和肉症风险 (OR=1.70,P=0.002) 之间发现了显著的正相关性.
- 随着TyG指数水平较高 (P<0.05) 萨科佩尼亚患病率增加.
- 线性回归显示了反向关联 (β=-0.03,P=0.020),ROC分析显示了TyG对肉类的强有力的预测能力 (AUC=0.685,P<0.001).
结论:
- 泰格指数表明,在患有CIAD的患者中,与肉症有积极的关联.
- 泰格指数可以作为一个有价值和可靠的生物标志物,用于预测这种患者群体中肉类的风险.
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