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重新利用FDA批准的药物对抗水病毒DNA依赖RNA聚合酶:虚拟查,正常模式分析和分子动力学模拟研究

Ahmad Abdul Salam Khan1, Muhammad Abrar Yousaf2, Jahanzaib Azhar3

  • 1Department of Biological Sciences, Virtual University of Pakistan, Lahore, Pakistan.

Virusdisease
|July 29, 2024
PubMed
概括

研究人员确定了尼洛替尼,康尼瓦普坦和波纳替尼作为潜在的药物来抑制麻疹病毒RNA聚合酶. 这些FDA批准的药物显示出通过药物重新定位来治疗麻疹疾病的前景.

关键词:
这种DNA依赖的RNA聚合酶是DNA依赖的.药物重新定位是药物重新定位.分子动力学模拟模型麻疹病毒的病毒.虚拟选是一个虚拟的选.

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