患有精神障碍的青少年的炎症性血液学比率:一个范围审查
Consortium psychiatricum
|July 29, 2024
概括
炎症性血液学比率 (IHRs) 与青少年心理健康状况有关. 较高的IHR与年轻人的症状严重程度增加,疾病的急性阶段和自我伤害行为相关.
科学领域:
- 血液学 血液学 血液学
- 精神病学是一个精神病学.
- 青少年医学 青少年医学
背景情况:
- 炎症性血液学比率 (IHRs),如中性粒细胞与淋巴细胞的比率,与成人心理健康有关.
- 青少年的证据有限,需要系统化.
研究的目的:
- 系统地审查和总结有关青少年精神障碍IHR的研究.
主要方法:
- 对10至19岁患有精神障碍 (不包括神经性厌食症) 患者的IHR研究进行范围审查.
- 在 MEDLINE 搜索到截至 2023 年 12 月 31 日的英语出版物.
- 基于外部 (健康对照) 或内部 (疾病阶段) 比较的分类研究.
主要成果:
- 包括11项横截面研究.
- 与对照组相比,患有精神障碍的青少年显示出更高的IHR.
- 较高的IHR与症状严重程度,躁狂发作,精神病恶化以及自我伤害/自杀行为相关.
结论:
- IHR与青少年精神障碍有关.
- 升高的IHRs表明更严重的临床表现.
- 需要进一步进行高质量的研究,以确定IHR作为诊断或预后生物标志物.
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