治疗神经髓炎光学谱系障碍的伊内比利苏马布治疗中的罕见不良反应:一个病例报告
Xuefen Chen1,2, Ziyan Shi3, Rui Wang3
1Department of Neurology, West China Xiamen Hospital of Sichuan University, Xiamen, China.
Therapeutic advances in neurological disorders
|July 29, 2024
概括
针对神经omyelitis optica光谱障碍 (NMOSD) 的CD19向疗法inebilizumab可以导致过渡性高CKaemia. 在NMOSD患者中,这种罕见的不良反应在停止单克隆抗体治疗后消失.
科学领域:
- 神经学 神经学
- 免疫学 免疫学 免疫学
- 药理学 药理学是指药理学的学科.
背景情况:
- 伊内比利祖马布是一种针对CD19的人性化单克隆抗体,已被批准用于水素-4免疫球蛋白G-血清阳性神经omyelitis optica光谱障碍 (NMOSD) 维持疗法.
- 常见的不良反应包括感染,输液反应和免疫球蛋白水平降低.
相关概念视频
01:20Myasthenia Gravis: Overview and Treatment
1.3K
Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
1.3K
01:15Myasthenia Gravis: Diagnostic Tests
730
Myasthenia gravis is an autoimmune condition affecting neuromuscular transmission, causing generalized weakness in skeletal muscles. Initial diagnoses rely on patients' signs, symptoms, and medical history. The challenge lies in distinguishing myasthenia from other muscular dystrophies. An important diagnostic feature is the significant improvement of symptoms after administering anticholinesterase inhibitors.
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
730