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Updated: Jun 18, 2025

In Vitro Bioluminescence Assay to Characterize Circadian Rhythm in Mammary Epithelial Cells
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通过食物传播的多环芳香碳水化合物和循环干扰

Yen-Chun Koh1, Min-Hsiung Pan1,2,3

  • 1Institute of Food Science and Technology, National Taiwan University, Taipei 106017, Taiwan.

ACS omega
|July 29, 2024
PubMed
概括

像PAHs这样的环境毒素可以通过激活基碳水化合物受体 (AhR) 来破坏昼夜节律,可能导致代谢疾病. 植物化学物质可能提供针对这种毒剂诱导的昼夜干扰的保护策略.

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The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent...
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