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研究基于Ca的生物医学材料的玻璃形成能力和腐蚀性能

Jing Feng¹, Yue Wang¹, Dehua Liu¹

¹1School of Materials Science and Engineering, North Minzu University, Yinchuan 750021, P.R. China.

Acta of bioengineering and biomechanics

|July 29, 2024

概括

新的基于的散装无形合金对生物植入物具有前景,具有类似骨的弹性和良好的生物相容性. Ca59Mg20Zn21合金表现出优越的耐腐蚀性,解决了永久金属植入物的关键挑战.

科学领域:

生物材料科学生物材料科学
材料工程材料工程材料工程
生物医学工程生物医学工程

背景情况:

永久金属植入物面临着诸如应力屏蔽和二次手术等挑战.
(Ca) - (Mg) - (Zn) 散装无形合金由于其类似骨的模量,生物相容性和降解性质,提供了一个有前途的替代品.
关于这些Ca-Mg-Zn合金的玻璃形成能力 (GFA) 和体内腐蚀的研究有限.

研究的目的:

研究不同 (Zn) 含量对Ca-Mg-Zn无形合金微观结构,玻璃形成能力 (GFA) 和生物腐蚀行为的影响.
评估这些合金作为潜在的生物医学材料的适用性.

主要方法:

开发了一种铜模喷涂造方法,以生产无形和无形晶体复合金条合金 (直径3毫米).
使用X射线衍射 (XRD) 描述了合金相.
通过电化学处理和浸泡试验评估腐蚀降解,并通过细胞毒性实验进行补充.

主要成果:

具有0-4% Zn (Ca53+xMg20Zn27-x) 的合金显示了Ca3Zn和CaZn2相的沉.
含6-10% Zn的合金是完全无形的.
Ca63Mg20Zn17表现出最好的玻璃形成能力 (GFA).
Ca59Mg20Zn21表现出优越的耐腐蚀性.
细胞毒性测试证实了Ca-Mg-Zn合金的良好生物相容性.

结论:

含量显著影响Ca-Mg-Zn合金的微观结构,GFA和耐腐蚀性.
Ca59Mg20Zn21合金由于其优越的耐腐蚀性和生物相容性,显示出生物医学应用的巨大潜力.
这些无形合金代表了传统金属植入物的可行替代品,可能克服应力屏蔽和二次手术的问题.

关键词:

腐蚀腐蚀是一种腐蚀.结晶化结晶化的过程.金属玻璃杯是一种金属玻璃杯.微观结构的微观结构

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