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[双极情绪障碍与精神药物治疗诱导的躁狂阶段发生]
A S Shteinberg1, A N Barkhatova1, A S Berezkin1
1Mental Health Research Centre, Moscow, Russia.
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
|July 29, 2024
概括
抗抑郁药可以触发躁狂阶段在双相情感障碍患者,需要谨慎的治疗策略. 研究正在发展,以个性化双相情感障碍护理,并尽量减少有害的副作用.
科学领域:
- 精神病学是一个精神病学.
- 药理学 药理学是指药理学的学科.
- 神经科学是一个神经科学.
背景情况:
- 自20世纪以来,人们已经认识到抗抑郁药引起的躁狂症在双相情感障碍中的风险.
- 在双相抑郁症中使用抗抑郁药可以导致诸如情绪转换和加速循环等不良影响.
研究的目的:
- 分析关于双相情感障碍中药物治疗诱导的躁狂阶段的历史发展和当前研究趋势.
- 探索对双相情感障碍的诊断和治疗的不断变化的观点,重点是尽量减少催产素效应.
主要方法:
- 通过使用关键词进行了全面的文献搜索,例如"药物诱导的躁狂"和"双相情感障碍".
- 出版物来源于PubMed/MEDLINE,俄罗斯引用索引和其他数据库,从19世纪中叶到现在.
主要成果:
- 历史观察强调抗抑郁药的风险导致情绪逆转和恶化双相患者的疾病过程.
- 最近的研究整合了临床,药理动力学,遗传学和神经生理学数据,以了解这些现象.
结论:
- 了解双极性障碍治疗的演变对于管理心理药物治疗诱导的躁狂阶段至关重要.
- 生物精神病学的进步为双相情感障碍的个性化医疗方法铺平了道路,旨在减少催产素并发症.
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