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Atypical antidepressants, including bupropion (Wellbutrin), mirtazapine (Remeron), nefazodone (Serzone), trazodone (Desyrel), and vilazodone (Viibryd), offer unique mechanisms of action. Bupropion weakly inhibits dopamine and norepinephrine reuptake, aiding depression treatment and smoking cessation, with a low risk of sexual dysfunction. Mirtazapine enhances serotonin and norepinephrine neurotransmission, leading to sedation, increased appetite, and weight gain. As a result, it helps treat...
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Antidepressant Drugs: Tricyclics, SSRIs, and SNRIs01:28

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Tricyclic Antidepressants (TCAs), including Desipramine (Norpramin), Imipramine (Tofranil), Clomipramine (Anafranil), and Amitriptyline (Elavil), inhibit serotonin and norepinephrine reuptake and also block other receptors. They are used for depression, pain conditions, and insomnia. Common adverse effects include anticholinergic effects, sedation, orthostatic hypotension, and weight gain. They have a narrow therapeutic window and so require plasma-level monitoring. Abrupt discontinuation can...
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Antidepressant Drugs: Overview01:25

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Antidepressant drugs are a class of medications primarily used for treating various mood disorders, including major depression, anxiety disorders, and other related conditions. These medicines work by modulating the neurotransmitter balance within the brain, alleviating depressive symptoms. Antidepressants can be broadly categorized into several groups according to their mechanism of action and chemical structure: Selective Serotonin Reuptake Inhibitors (SSRIs), Serotonin-Norepinephrine...
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Drug Therapy01:28

Drug Therapy

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The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
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Electroconvulsive Therapy01:30

Electroconvulsive Therapy

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Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
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Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
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[About the causes and therapy of depressive disorders in COVID-19].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2021
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[精神病学实践中的抗抑郁药]

E Yu Abritalin1, I Yu Khabarov1

  • 1Almazov National Medical Research Centre, St. Petersburg, Russia.

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
|July 29, 2024
PubMed
概括

选择性血清素再吸收抑制剂通常用于心理健康状况. 其他抗抑郁药用于更严重的病例或当初始治疗无效时,治疗持续时间差异很大.

科学领域:

  • 精神病学是一个精神病学.
  • 药理学 药理学是指药理学的学科.
  • 临床医学 临床医学

背景情况:

  • 选择性血清素再吸收抑制剂 (SSRI) 经常被推用于抑郁症和神经障碍.
  • 其他类型的抗抑郁药,包括血清 - 上腺素再吸收抑制剂 (SNRIs),三环,四环和单胺氧化酶抑制剂,仅适用于耐治疗或严重的疾病.
  • 长期抗抑郁药物治疗,跨越几个月到几年,是常见的,当耐受良好时.

研究的目的:

  • 分析抗抑郁药在抑郁症和神经性疾病的选择标准.
  • 审查各种类型抗抑郁药的临床应用和疗效.
  • 突出Canonpharma生产的特定抗抑郁药,强调它们的生物等价性和治疗应用.

主要方法:

  • 对抗抑郁药选择临床建议的分析.
  • 对不同抗抑郁药组的药理机制的审查.
  • 讨论使用特定Canonpharma生产抗抑郁药的临床经验.
  • 对Canonpharma生产的通用抗抑郁药的生物等价性研究的评估.

主要成果:

  • SSRI是最常用的抗抑郁药,符合临床指南.
  • 其他类型的抗抑郁药用于SSRI反应不足或严重的症状.
关键词:
亚戈梅拉丁是一种非药物.抑郁 抑郁症 抑郁症 抑郁症 是一种杜洛克赛丁 (duloxetine) 是一种药物.埃斯基塔洛普拉姆 (escitalopram) 是一种药物.克塞提因 (fluoxetine) 是一种含有素的药物.米尔塔扎因 (Mirtazapine) 是一种药物.神经性障碍 神经性障碍 神经性障碍谢特拉林 (Sertraline) 是一种可怕的药物.

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  • 佳能制药生产提供了一系列抗抑郁药 (塞特拉林,素,埃斯基塔洛普拉姆,杜洛克赛丁,米尔塔扎平,阿戈梅拉丁) 已被证明具有生物等价性.
  • 这些药物有效治疗各种抑郁和精神障碍.

    • 结论:

    • 选择抗抑郁药取决于疾病的严重程度和治疗反应.
    • 佳能药业生产的抗抑郁药因已证明的生物等价性而提供可靠的治疗选择.
    • 对抗抑郁药的机制和临床指导方针的全面理解可以确保最佳的患者护理.