荷兰糖尿病门诊患者的死亡率模式
Jessica C G Bak1,2, Silvia A G de Vries1,2, Erik H Serné1
1Department of Vascular Medicine, Amsterdam University Medical Centers, Amsterdam, Netherlands.
Diabetes, obesity & metabolism
|July 29, 2024
概括
荷兰门诊糖尿病患者的死亡率很高,尤其是2型糖尿病患者. 吸烟和功能衰竭显著增加死亡风险,强调了早期干预的必要性.
科学领域:
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 糖尿病是全球死亡的主要原因之一.
- 与一般实践相比,糖尿病门诊患者的并发症率较高.
- 关于糖尿病门诊患者的特定死亡模式的研究有限.
研究的目的:
- 调查荷兰糖尿病门诊患者的死亡率,死亡原因和相关预测因素.
- 分析特定类型糖尿病 (1型和2型) 的死亡率趋势.
- 确定导致该人口死亡率的风险因素.
主要方法:
- 一项队列研究利用了2016-2020年荷兰儿科和成人糖尿病登记处 (DPARD) 的数据.
- 将DPARD数据与荷兰统计局 (CBS) 联系起来,以获得全面的死亡率,种族和教育信息.
- 使用考克斯比例危险回归来估计所有原因和心血管死亡率.
主要成果:
- 观察到高死亡率:成人1型糖尿病为每1万人年67.7,2型糖尿病为324.2.
- 恶性病是非心血管死亡的主要原因.
- 死亡率在流行病年 (2018年流感,2020年COVID-19) 达到峰值.
- 所有原因死亡的关键预测因素包括年龄,吸烟和功能受损 (eGFR <60毫升/分钟).
- 2型糖尿病死亡率的其他危险因素包括男性性别,低BMI,糖尿病持续时间短,高血压.
结论:
- 荷兰糖尿病门诊患者的死亡率较高.
- 吸烟和功能衰竭是两种糖尿病类型的显著死亡率预测因素.
- 早期发现和管理已识别的风险因素对于改善糖尿病护理的临床结果至关重要.
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