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Updated: Jun 18, 2025

Synthesis of Protein Bioconjugates via Cysteine-maleimide Chemistry
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替代的马利米德:在生物结合,材料科学和纳米技术中的自我报告的链接器和标签

Jake E Barker1, Joshua D Tibbetts1, Calum T J Ferguson1

  • 1School of Chemistry, University of Birmingham, Birmingham, B15 2TT, UK.

Angewandte Chemie (International ed. in English)
|July 29, 2024
PubMed
概括

替代的maleimides是多功能光探头. 它们的可调节性质可以为材料标签和药物输送等应用程序提供实时环境反.

关键词:
光材料是一种光材料.大分子合的结合.自报告的链接器链接器小分子光剂的小分子光剂.替代的马莱米化物

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Proteins are involved in several cellular processes and biochemical reactions. Analyzing a specific protein of interest requires it to be isolated from the other proteins in the cell. This is achieved by overexpressing the specific gene in a suitable host to produce large quantities of the target protein. A tag or label is recombined with the gene to produce a fusion protein containing the target protein and the tag. The tags on these fusion proteins can then be used for easy detection and...
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