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对膀癌患者的泌尿膀微生物组的综述,以及它对膀病变发生的含义

Panagiotis Velissarios Stamatakos¹, Charalampos Fragkoulis², Ieronymos Zoidakis³

¹Department of Urology, General Hospital of Athens "G. Gennimatas", Leof. Mesogeion 154, Athens, 115 27, Greece. pvstamatakos@gmail.com.

World journal of urology

|July 29, 2024

概括

尿路微生物组或尿管组越来越多地研究其在膀癌中的作用. 虽然初步数据表明它与膀瘤发生有关,但需要更多的研究来证实它的病原学,预后和治疗影响.

科学领域:

泌尿器科泌尿器科泌尿器科泌尿器科
微生物学微生物学
在瘤学瘤学.

背景情况:

尿路微生物组是一个新发现的研究领域.
预先的数据表明,多巴组可能在膀癌的发展和预后中发挥作用.

研究的目的:

审查目前关于膀癌患者与健康个体尿道微生物组合的证据.
探索多巴基因组在膀泌尿器癌中的潜在影响.

主要方法:

通过使用PubMed/MEDLINE,Scopus和Cochrane图书馆进行了全面的文献审查,直到2023年12月.
搜索术语包括"尿道微生物群"和"尿道微生物群".
选择了以英语出版的比较膀癌患者和健康对照者的尿道微生物组的研究.

主要成果:

总共有2,356份报告被确定,其中16篇文章符合纳入标准.
选择的研究分析了大约486名膀癌患者的数据.
通过培养和基于分子的技术实现了尿道和膀的微生物特征.

结论:

尿道和膀被微生物殖民.
当前文献的局限性降低了现有报道的可靠性.
尿路微生物组代表了膀癌研究的一个有希望的领域,有越来越多的证据表明其病原遗传,预后和治疗作用.

关键词:

膀癌是一种癌症.尿路微生物群是什么意思尿液中的微生物群.乌罗生物组是人类的生命体.

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