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Updated: Jun 18, 2025

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来自海洋海绵的类化合物抑制PI3K/AKT/mTOR信号通路,以对抗扩散性大B细胞淋巴瘤

Jie Liu1, Yung-Ting Chang1, Yan-Yu Kou1

  • 1Department of Pharmacy, Research Center for Marine Drugs, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, China.

Medical oncology (Northwood, London, England)
|July 29, 2024
PubMed
概括

一种新的海洋天然产品模拟物AP-48显示出强大的抗癌作用,对扩散性大B细胞淋巴瘤 (DLBCL) 有效. 它有效地抑制DLBCL细胞生长,诱导细胞亡,并在临床前模型中显示治疗潜力.

关键词:
亚普坦胺是一种阿普坦胺.扩散性大B细胞淋巴瘤 (DLBCL)海洋海绵是一种海绵.PI3K/AKT 信号通道 信号通道

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